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1620758-33-9
- Product Name:Empagliflozin α-isomer
- Molecular Formula:
- Purity:99%
- Molecular Weight:450.916
Product Details;
CasNo: 1620758-33-9
Manufacturer supply top purity Empagliflozin α-isomer 1620758-33-9 with GMP standards
- Molecular Formula:C23H27ClO7
- Molecular Weight:450.916
- Boiling Point:664.5±55.0 °C(Predicted)
- PKA:13.23±0.70(Predicted)
- Density:1.398±0.06 g/cm3(Predicted)
1620758-33-9 Relevant articles
New Glyflozin Synthesis Method in a Continuous Reaction Process
-
Paragraph 0281; 0282; 0289-0292; 0299-0301, (2021/09/07)
The present invention relates to a metho...
IMPROVED PROCESS FOR THE PREPARATION OF EMPAGLIFLOZIN AND ITS CRYSTALLINE POLYMORPH
-
Page/Page column 4; 9-11, (2021/12/31)
The present invention relates to an impr...
Preparation method of SGLT-2 inhibitor and intermediate
-
, (2021/05/19)
The invention discloses a preparation me...
Synthetic method of empagliflozin
-
Paragraph 0029-0033, (2021/07/24)
The invention belongs to the technical f...
1620758-33-9 Process route
-
-
C51H49ClO7

-
-
864070-44-0,1620758-33-9,864070-43-9
empagliflozin
Conditions | Yield |
---|---|
With
hydrogen;
In
ethanol;
at 75 - 80 ℃;
for 20h;
under 6000.6 - 6750.68 Torr;
Solvent;
Inert atmosphere;
Autoclave;
|
93.7% |
-
-
864070-37-1
(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

-
-
219823-47-9
(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

-
-
864070-44-0,1620758-33-9,864070-43-9
empagliflozin
Conditions | Yield |
---|---|
With
caesium carbonate;
In
N,N-dimethyl-formamide;
at 75 ℃;
for 21h;
|
57% |
With
caesium carbonate;
In
N,N-dimethyl-formamide;
at 75 ℃;
for 18h;
|
49% |
With
caesium carbonate;
In
N,N-dimethyl-formamide;
at 75 ℃;
for 18h;
|
49% |
With
caesium carbonate;
at 25 - 40 ℃;
|
|
With
caesium carbonate;
In
N,N-dimethyl-formamide;
at 30 - 45 ℃;
for 24h;
|
0.55 kg |
1620758-33-9 Upstream products
-
(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
-
toluene-4-sulfonic acid (S)-(tetrahydrofuran-3-yl)ester
-
(R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate
-
methyl-1-C-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucopyranoside
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