Product Classification
- drug impurity
- drug standards
- Metaraminol bitartrate
- analytical chemistry
- standard substances
- chemical custom synthesis
- Azithromycin
- Atorvastatin
- (S)-Cinacalcet
- Ilaprazole
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- Duloxetine
- Octreotide
- Budesonide
- Carboprost Trometamol
- Minocycline
- Dobutamine
- Netupitant
- Axitinib
- Omadacycline
- Brivaracetam
- Metoprolol
- Indobufen
- Empagliflozin
- Dapagliflozin
- Acetylcysteine
- Hydroxychloroquine
- Tegoprazan
- Lenalidomide
- Canagliflozin
- Bromocriptine
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- Bisoprolol
- Rocuronium Bromide
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- Bumetanide
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Contact us
Tel：+86 17320513646
Phone：+86 17320513646
Website：https://www.moxinchem.com
Email： mike@molcoo.com
Address：Room 005, 15th Floor, Building D2, Phase III, Software New Town, No. 8 Huacheng Avenue, East Lake High-tech Development Zone, Wuhan, Hubei Province, China
56718-76-4
- Product Name：Metoprolol USP Impurity B
- Molecular Formula：C12H17ClO3
- Purity：99%
- Molecular Weight：244.718
Product Details;
CasNo： 56718-76-4
Molecular Formula： C12H17ClO3
Manufacturer supply good quality Metoprolol USP Impurity B 56718-76-4 with stock
- Molecular Formula:C12H17ClO3
- Molecular Weight:244.718
- Vapor Pressure:5.95E-06mmHg at 25°C
- Refractive Index:1.521
- Boiling Point:364.5°C at 760 mmHg
- PKA:13.12±0.20(Predicted)
- Flash Point:174.2°C
- PSA：38.69000
- Density:1.157g/cm3
- LogP:1.85400
rac 1-Chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol(Cas 56718-76-4) Usage
InChI:InChI=1/C12H17ClO3/c1-15-7-6-10-2-4-12(5-3-10)16-9-11(14)8-13/h2-5,11,14H,6-9H2,1H3
56718-76-4 Relevant articles
Method for preparing metoprolol succinate
-
Paragraph 0036-0037; 0039-0040; 0042-0043; 0045-0046, (2020/09/16)
The invention relates to a method for pr...
Kinetic resolution of (: RS)-1-chloro-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol: a metoprolol intermediate and its validation through homology model of Pseudomonas fluorescens lipase
Soni, Surbhi-,Dwivedee, Bharat P.,Sharma, Vishnu K.,Banerjee, Uttam C.
, p. 36566 - 36574 (2017/08/02)
In the present study Pseudomonas fluores...
Continuous and convergent access to vicinyl amino alcohols
Nobuta, Tomoya,Xiao, Guozhi,Ghislieri, Diego,Gilmore, Kerry,Seeberger, Peter H.
supporting information, p. 15133 - 15136 (2015/10/12)
Five active pharmaceutical ingredients (...
Chemoenzymatic synthesis of the potential antihypertensive agent (2R,2′S)-β-hydroxyhomometoprolol
Regla, Ignacio,Luviano-Jardon, Axel,Demare, Patricia,Hong, Enrique,Torres-Gavilan, Alejandro,Lopez-Munguia, Agustin,Castillo, Edmundo
experimental part, p. 2439 - 2442 (2009/04/11)
The kinetic resolution of 1-chloro-3-[4-...
56718-76-4 Process route
-
-
56718-71-9
4-(2-methoxyethyl)phenol
-
-
106-89-8,24969-06-0,13403-37-7
epichlorohydrin
-
![2-[4-(2'-methoxyethyl)phenoxymethyl]oxirane](/upload/2024/12/431d633e-f754-4139-99c1-0bd529266607.png)
-
56718-70-8
2-[4-(2'-methoxyethyl)phenoxymethyl]oxirane
-
![(+/-)-1-[4-(2-methoxyethyl)phenoxy]-3-chloro-2-propanol](/upload/2024/12/1b49047b-c4ad-4184-8c67-ec4ba1548f0f.png)
-
56718-76-4
(+/-)-1-[4-(2-methoxyethyl)phenoxy]-3-chloro-2-propanol
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
|
90% 10% |
|
4-(2-methoxyethyl)phenol;
With
potassium hydroxide;
In
methanol;
at 40 - 45 ℃;
for 1h;
epichlorohydrin;
at 40 ℃;
for 24h;
|
|
|
With
sodium hydroxide;
In
water;
at 30 - 40 ℃;
for 5h;
Temperature;
|
-
-
56718-70-8
2-[4-(2'-methoxyethyl)phenoxymethyl]oxirane
-
-
56718-76-4
(+/-)-1-[4-(2-methoxyethyl)phenoxy]-3-chloro-2-propanol
| Conditions | Yield |
|---|---|
|
With
morpholine; 1,3,5-trichloro-2,4,6-triazine;
In
water;
at 20 ℃;
for 0.5h;
|
98% |
|
2-[4-(2'-methoxyethyl)phenoxymethyl]oxirane;
With
β‐cyclodextrin;
In
water; acetone;
at 60 ℃;
With
thionyl chloride;
In
water; acetone;
at 20 ℃;
for 10h;
|
91% |
|
With
zirconyl chloride;
In
acetonitrile;
at 20 ℃;
for 1.16667h;
|
80% |
|
With
water; acetyl chloride;
In
dichloromethane;
for 12h;
|
56718-76-4 Upstream products
-
56718-71-9
4-(2-methoxyethyl)phenol
-
106-89-8
epichlorohydrin
-
56718-70-8
2-[4-(2'-methoxyethyl)phenoxymethyl]oxirane
-
2491-38-5
2-bromo-1-(4'-hydroxyphenyl)-1-ethanone
56718-76-4 Downstream products
-
1017859-19-6
Acetic acid 1-chloromethyl-2-[4-(2-methoxy-ethyl)-phenoxy]-ethyl ester
-
1107647-82-4
(2S)-1-chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propyl stearate
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