Product Classification
- drug impurity
- drug standards
- Metaraminol bitartrate
- analytical chemistry
- standard substances
- chemical custom synthesis
- Azithromycin
- Atorvastatin
- (S)-Cinacalcet
- Ilaprazole
- Tranexamic Acid
- Duloxetine
- Octreotide
- Budesonide
- Carboprost Trometamol
- Minocycline
- Dobutamine
- Netupitant
- Axitinib
- Omadacycline
- Brivaracetam
- Metoprolol
- Indobufen
- Empagliflozin
- Dapagliflozin
- Acetylcysteine
- Hydroxychloroquine
- Tegoprazan
- Lenalidomide
- Canagliflozin
- Bromocriptine
- Rasagiline
- Bortezomib
- Diclofenac
- Bisoprolol
- Rocuronium Bromide
- Esmolol
- Bromhexine
- Probucol
- Formoterol
- Crisaborole
- Pitavastatin (3S,5S)-Isomer Calcium
- Bumetanide
- Dotinurad
- Fulvestrant
- Dotinurad
- Landiolol
Contact us
Tel：+86 17320513646
Phone：+86 17320513646
Website：https://www.moxinchem.com
Email： mike@molcoo.com
Address：Room 005, 15th Floor, Building D2, Phase III, Software New Town, No. 8 Huacheng Avenue, East Lake High-tech Development Zone, Wuhan, Hubei Province, China
63095-51-2
- Product Name：Brivaracetam Impurity
- Molecular Formula：C7H12O2
- Purity：99%
- Molecular Weight：128.171
Product Details;
CasNo： 63095-51-2
Molecular Formula： C7H12O2
Manufacturer supply high quality Brivaracetam Impurity 63095-51-2 with GMP standards
- Molecular Formula:C7H12O2
- Molecular Weight:128.171
- Boiling Point:226.3±8.0 °C(Predicted)
- PSA：26.30000
- Density:0.983±0.06 g/cm3(Predicted)
- LogP:1.34960
63095-51-2 Relevant articles
Preparation method of brivaracetam intermediate
-
Paragraph 0025; 0070-0071, (2021/09/04)
The invention provides a preparation met...
Preparation method of brivaracetam intermediate
-
Paragraph 0102-0107, (2021/06/12)
The invention relates to a preparation m...
COMPOUND AND USE THEREOF IN SYNTHESIS OF BRIVARACETAM INTERMEDIATE AND CRUDE DRUG
-
Page/Page column 0095, (2021/08/27)
The present application provides a compo...
Synthesis and olfactory evaluation of optically active β-alkyl substituted γ-lactones and whiskey lactone analogues
Kato, Daiki,Kawasaki, Masashi,Morita, Yuko,Okada, Takuya,Tanaka, Yasuo,Toyooka, Naoki
, (2020/02/22)
Optically active β-alkyl substituted γ-l...
63095-51-2 Process route
-
-
21963-27-9
4-propyl-5H-furan-2-one
-
-
63095-51-2
(+)-(R)-4-propyl-4,5-dihydrofuran-2(3H)-one
| Conditions | Yield |
|---|---|
|
With
bis(η5-cyclopentadienyl)ruthenium; (R,R)-(+)-2,2'-isopropylidene bis(4-isopropyl-2-oxazoline); hydrogen;
In
methanol;
at 50 ℃;
under 15001.5 Torr;
Temperature;
Pressure;
Solvent;
Reagent/catalyst;
Autoclave;
|
93% |
|
With
water; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); copper(l) chloride; sodium t-butanolate;
In
toluene; tert-butyl alcohol;
at 0 - 30 ℃;
Inert atmosphere;
|
79.63% |
|
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 20 °C / 9000.9 Torr
2: sodium hydroxide / water / 2 h / 30 °C
With
palladium 10% on activated carbon; hydrogen; sodium hydroxide;
In
methanol; water;
|
|
|
Multi-step reaction with 4 steps
1: palladium 10% on activated carbon; hydrogen / ethanol / 9 h / 20 °C / 225.02 - 375.04 Torr / Large scale
2: sodium hydroxide / ethanol / 1 h / 20 °C / Large scale
3: 0.5 h / 20 °C / Large scale
4: hydrogenchloride / water / 3 h / 20 - 60 °C / Large scale
With
hydrogenchloride; palladium 10% on activated carbon; hydrogen; sodium hydroxide;
In
ethanol; water;
|
-
-
C7H14O3
-
-
63095-51-2
(+)-(R)-4-propyl-4,5-dihydrofuran-2(3H)-one
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
water;
at 20 ℃;
pH=3;
|
77% |
|
With
toluene-4-sulfonic acid;
In
toluene;
for 20h;
Reflux;
|
12 g |
|
With
toluene-4-sulfonic acid;
In
toluene;
Reflux;
|
7.8 g |
|
With
toluene-4-sulfonic acid;
In
toluene;
Reflux;
|
12 g |
|
With
toluene-4-sulfonic acid;
In
toluene;
at 20 ℃;
Reflux;
|
12 g |
|
With
trifluoroacetic acid;
In
toluene;
at 20 - 30 ℃;
|
63095-51-2 Upstream products
-
123975-96-2
cis-4-propyl-5-p-tolylthio-4,5-dihydrofuran-2(3H)-one
-
147725-41-5
(2R)-2-propyl-3-(1,3-dithian-2-ylidene)propanol
-
147725-30-2
(4R,5S)-3-<1-oxo-3-(1,3-dithian-2-ylidene)-2-propylpropyl>-4-methyl-5-phenyl-2-oxazolidinone
-
75291-15-5
(2S,3S)-(E)-butylidene-3,4-dimethyl-2-phenyl-[1,4]oxazepane-5,7-dione
63095-51-2 Downstream products
-
910134-80-4
3-(3-methoxy-benzyl)-4-propyl-dihydro-furan-2-one
-
357336-20-0
brivaracetam
-
357337-00-9
((2R)-2-[(4R)-2-oxo-4-propyltetrahydro-1H-pyrrol-1-yl]butanamide)
-
357336-99-3
((2S)-2-[(4S)-2-oxo-4-propyltetrahydro-1H-pyrrol-1-yl]butanamide)
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