What is the (S)-Cinacalcet hydrochloride?

(S)-Cinacalcet hydrochloride is , while it's Molecular Formula is C 22 H 22 F 3 N*(x)ClH. Used in Pharmaceutical Industry: (S)-Cinacalcet hydrochloride is used as a therapeutic agent for managing conditions such as chronic kidney disease and hyperparathyroidism. It is employed to regulate the body's production of parathyroid hormone, thereby controlling calcium levels in the blood and bones, which is crucial for the health of patients with these conditions. Used in Chronic Kidney Disease Treatment: (S)-Cinacalcet hydrochloride is used as a medication to treat secondary hyperparathyroidism in patients with chronic kidney disease who are on dialysis. Its calcimimetic action helps to maintain calcium and phosphorus levels within the desired range, reducing the risk of complications associated with abnormal calcium metabolism. Used in Hyperparathyroidism Management: (S)-Cinacalcet hydrochloride is used as a treatment for primary hyperparathyroidism, a condition characterized by the overproduction of parathyroid hormone. By increasing the sensitivity of the calcium-sensing receptor to extracellular calcium, it helps to normalize parathyroid hormone levels and associated calcium imbalances.

What is the CAS number for (S)-Cinacalcet hydrochloride?

The CAS number of (S)-Cinacalcet hydrochloride is 1217809-88-5.

What is (S)-Cinacalcet hydrochloride (1217809-88-5) used for?

(S)-Cinacalcet hydrochloride, commonly known as Cinacalcet, is a synthetic, hydrochloride salt form of cinacalcet with calcimimetic activity. It functions by mimicking the action of calcium on tissues in the body, primarily by enhancing the sensitivity of the calcium-sensing receptor (CaSR) to extracellular calcium. This action leads to the regulation of the body's production of parathyroid hormone, which in turn helps control calcium levels in the blood and bones. (S)-Cinacalcet hydrochloride is typically administered orally and is characterized by a bitter taste.

What is the (S)-Cinacalcet hydrochloride?

(S)-Cinacalcet hydrochloride is , while it's Molecular Formula is C 22 H 22 F 3 N*(x)ClH. Used in Pharmaceutical Industry: (S)-Cinacalcet hydrochloride is used as a therapeutic agent for managing conditions such as chronic kidney disease and hyperparathyroidism. It is employed to regulate the body's production of parathyroid hormone, thereby controlling calcium levels in the blood and bones, which is crucial for the health of patients with these conditions. Used in Chronic Kidney Disease Treatment: (S)-Cinacalcet hydrochloride is used as a medication to treat secondary hyperparathyroidism in patients with chronic kidney disease who are on dialysis. Its calcimimetic action helps to maintain calcium and phosphorus levels within the desired range, reducing the risk of complications associated with abnormal calcium metabolism. Used in Hyperparathyroidism Management: (S)-Cinacalcet hydrochloride is used as a treatment for primary hyperparathyroidism, a condition characterized by the overproduction of parathyroid hormone. By increasing the sensitivity of the calcium-sensing receptor to extracellular calcium, it helps to normalize parathyroid hormone levels and associated calcium imbalances.

What is the CAS number for (S)-Cinacalcet hydrochloride?

The CAS number of (S)-Cinacalcet hydrochloride is 1217809-88-5.

What is (S)-Cinacalcet hydrochloride (1217809-88-5) used for?

(S)-Cinacalcet hydrochloride, commonly known as Cinacalcet, is a synthetic, hydrochloride salt form of cinacalcet with calcimimetic activity. It functions by mimicking the action of calcium on tissues in the body, primarily by enhancing the sensitivity of the calcium-sensing receptor (CaSR) to extracellular calcium. This action leads to the regulation of the body's production of parathyroid hormone, which in turn helps control calcium levels in the blood and bones. (S)-Cinacalcet hydrochloride is typically administered orally and is characterized by a bitter taste.

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1217809-88-5

Product Name：(S)-Cinacalcet Hydrochloride
Molecular Formula：C22H22F3N.HCl
Purity：99%
Molecular Weight：393.8729296

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Product Details;

CasNo： 1217809-88-5

Molecular Formula： C22H22F3N.HCl

Factory Sells Best Quality (S)-Cinacalcet Hydrochloride 1217809-88-5 with steady supply

Molecular Formula:C₂₂H₂₂F₃N*(x)ClH
Molecular Weight:393.8729296
PSA：12.03000
LogP:7.33490

1217809-88-5 Relevant articles

Hydroxoiridium-Catalyzed Hydroalkylation of Terminal Alkenes with Ureas by C(sp3)?H Bond Activation

Yamauchi, Daisuke,Nishimura, Takahiro,Yorimitsu, Hideki

, p. 7200 - 7204 (2017)

Direct alkylation of a methyl group, on ...

Hydrochloric cinacalcet preparation method

-

, (2017/08/29)

The invention discloses a hydrochloric c...

1217809-88-5 Process route

: C₂₀H₂₀N₂O

: 1217809-88-5
N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: [(1,5-cyclooctadiene)(OH)iridium(I)]2; 1,1'-(1,2-phenylene)bis[1,1-bis(1-methylethyl)phosphine]; potassium trimethylsilonate / toluene / 20 h / 80 °C / Inert atmosphere; Schlenk technique 2.1: potassium hydroxide / dimethyl sulfoxide; water / 12 h / 120 °C / Inert atmosphere; Schlenk technique 2.2: 20 °C / Inert atmosphere; Schlenk technique With [(1,5-cyclooctadiene)(OH)iridium(I)]2; 1,1'-(1,2-phenylene)bis[1,1-bis(1-methylethyl)phosphine]; potassium trimethylsilonate; potassium hydroxide; In water; dimethyl sulfoxide; toluene;

Yield

Multi-step reaction with 2 steps

1.1: [(1,5-cyclooctadiene)(OH)iridium(I)]2; 1,1'-(1,2-phenylene)bis[1,1-bis(1-methylethyl)phosphine]; potassium trimethylsilonate / toluene / 20 h / 80 °C / Inert atmosphere; Schlenk technique

2.1: potassium hydroxide / dimethyl sulfoxide; water / 12 h / 120 °C / Inert atmosphere; Schlenk technique

2.2: 20 °C / Inert atmosphere; Schlenk technique

With [(1,5-cyclooctadiene)(OH)iridium(I)]2; 1,1'-(1,2-phenylene)bis[1,1-bis(1-methylethyl)phosphine]; potassium trimethylsilonate; potassium hydroxide; In water; dimethyl sulfoxide; toluene;

: 15297-33-3,20218-55-7,42882-32-6,98978-55-3
(S)-N-methyl-N-1-(1-naphthyl)ethyl amine

: 1217809-88-5
N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: dichloromethane 2.1: [(1,5-cyclooctadiene)(OH)iridium(I)]2; 1,1'-(1,2-phenylene)bis[1,1-bis(1-methylethyl)phosphine]; potassium trimethylsilonate / toluene / 20 h / 80 °C / Inert atmosphere; Schlenk technique 3.1: potassium hydroxide / dimethyl sulfoxide; water / 12 h / 120 °C / Inert atmosphere; Schlenk technique 3.2: 20 °C / Inert atmosphere; Schlenk technique With [(1,5-cyclooctadiene)(OH)iridium(I)]2; 1,1'-(1,2-phenylene)bis[1,1-bis(1-methylethyl)phosphine]; potassium trimethylsilonate; potassium hydroxide; In dichloromethane; water; dimethyl sulfoxide; toluene;

Yield

Multi-step reaction with 3 steps

1.1: dichloromethane

2.1: [(1,5-cyclooctadiene)(OH)iridium(I)]2; 1,1'-(1,2-phenylene)bis[1,1-bis(1-methylethyl)phosphine]; potassium trimethylsilonate / toluene / 20 h / 80 °C / Inert atmosphere; Schlenk technique

3.1: potassium hydroxide / dimethyl sulfoxide; water / 12 h / 120 °C / Inert atmosphere; Schlenk technique

3.2: 20 °C / Inert atmosphere; Schlenk technique

With [(1,5-cyclooctadiene)(OH)iridium(I)]2; 1,1'-(1,2-phenylene)bis[1,1-bis(1-methylethyl)phosphine]; potassium trimethylsilonate; potassium hydroxide; In dichloromethane; water; dimethyl sulfoxide; toluene;

1217809-88-5 Upstream products

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1217809-88-5 Downstream products

1301700-82-2
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1217809-88-5

Product Details;

Factory Sells Best Quality (S)-Cinacalcet Hydrochloride 1217809-88-5 with steady supply

1217809-88-5 Relevant articles

Hydroxoiridium-Catalyzed Hydroalkylation of Terminal Alkenes with Ureas by C(sp3)?H Bond Activation

Yamauchi, Daisuke,Nishimura, Takahiro,Yorimitsu, Hideki

, p. 7200 - 7204 (2017)

Hydrochloric cinacalcet preparation method

-

, (2017/08/29)

1217809-88-5 Process route

1217809-88-5 Upstream products

1217809-88-5 Downstream products

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