What is the Axitinib Impurity 4?

Axitinib Impurity 4 is , while it's Molecular Formula is C 22 H 20 N 4 OS.

What is the CAS number for Axitinib Impurity 4?

The CAS number of Axitinib Impurity 4 is 1443118-73-7.

What is Axitinib Impurity 4 (1443118-73-7) used for?

Axitinib Impurity 4, also known as N-desmethyl axitinib, is a chemical compound that serves as an impurity reference standard for the anti-cancer drug Axitinib. It plays a crucial role in ensuring the safety and efficacy of the drug by being used for quality control and testing purposes in pharmaceutical manufacturing. Used in Pharmaceutical Industry: Axitinib Impurity 4 is used as a reference standard for: 1. Quality Control: It helps in monitoring and controlling the levels of impurities in drug products to ensure their safety and efficacy for patients. 2. Analytical Testing: It is utilized for various analytical methods to determine the purity and potency of the active pharmaceutical ingredient (API) in Axitinib. 3. Quality Assurance: It aids in the development, validation, and routine testing of pharmaceutical products, ensuring that they meet the required standards and specifications.

What is the Axitinib Impurity 4?

Axitinib Impurity 4 is , while it's Molecular Formula is C 22 H 20 N 4 OS.

What is the CAS number for Axitinib Impurity 4?

The CAS number of Axitinib Impurity 4 is 1443118-73-7.

What is Axitinib Impurity 4 (1443118-73-7) used for?

Axitinib Impurity 4, also known as N-desmethyl axitinib, is a chemical compound that serves as an impurity reference standard for the anti-cancer drug Axitinib. It plays a crucial role in ensuring the safety and efficacy of the drug by being used for quality control and testing purposes in pharmaceutical manufacturing. Used in Pharmaceutical Industry: Axitinib Impurity 4 is used as a reference standard for: 1. Quality Control: It helps in monitoring and controlling the levels of impurities in drug products to ensure their safety and efficacy for patients. 2. Analytical Testing: It is utilized for various analytical methods to determine the purity and potency of the active pharmaceutical ingredient (API) in Axitinib. 3. Quality Assurance: It aids in the development, validation, and routine testing of pharmaceutical products, ensuring that they meet the required standards and specifications.

Product Classification

Contact us

Tel：+86 17320513646

Phone：+86 17320513646

Website：https://www.moxinchem.com

Email： mike@molcoo.com

Address：Room 005, 15th Floor, Building D2, Phase III, Software New Town, No. 8 Huacheng Avenue, East Lake High-tech Development Zone, Wuhan, Hubei Province, China

1443118-73-7

Product Name：Axitinib Impurity
Molecular Formula：
Purity：99%
Molecular Weight：388.493

Inquiry

Product Details;

CasNo： 1443118-73-7

Manufacturer supply high quality Axitinib Impurity 1443118-73-7 with ISO standards

Molecular Formula:C₂₂H₂₀N₄OS
Molecular Weight:388.493

1443118-73-7 Relevant articles

Preparation method of drug Axitinib for resisting kidney cancer

-

, (2018/05/16)

The invention discloses a preparation me...

1443118-73-7 Process route

: C₈H₈NOS^(1-)*Na⁽¹⁺⁾

: C₁₄H₁₂ClN₃

: 1443118-73-7
C₂₂H₂₀N₄OS

Conditions

Conditions	Yield
for 1h; Heating;	65.52 g

: 116570-49-1
3-chloro-6-hydroxy-1H-indazole

: 1443118-73-7
C₂₂H₂₀N₄OS

Conditions

Conditions	Yield
Multi-step reaction with 8 steps 1: sodium hydroxide; dimethyl sulfate 2: sodium; magnesium / diethyl ether / Heating 3: hydrogenchloride; zinc(II) chloride / water / Heating 4: 2 h / 300 °C / Sealed tube 5: hydrogen iodide 6: iron(III) chloride; sulfuric acid / water 7: trichlorophosphate; trifluoromethylsulfonic anhydride 8: 1 h / Heating With hydrogenchloride; iron(III) chloride; trifluoromethylsulfonic anhydride; sulfuric acid; hydrogen iodide; sodium; magnesium; dimethyl sulfate; sodium hydroxide; zinc(II) chloride; trichlorophosphate; In diethyl ether; water;

Yield

Multi-step reaction with 8 steps

1: sodium hydroxide; dimethyl sulfate

2: sodium; magnesium / diethyl ether / Heating

3: hydrogenchloride; zinc(II) chloride / water / Heating

4: 2 h / 300 °C / Sealed tube

5: hydrogen iodide

6: iron(III) chloride; sulfuric acid / water

7: trichlorophosphate; trifluoromethylsulfonic anhydride

8: 1 h / Heating

With hydrogenchloride; iron(III) chloride; trifluoromethylsulfonic anhydride; sulfuric acid; hydrogen iodide; sodium; magnesium; dimethyl sulfate; sodium hydroxide; zinc(II) chloride; trichlorophosphate; In diethyl ether; water;

1443118-73-7 Upstream products

116570-49-1
3-chloro-6-hydroxy-1H-indazole
362512-38-7
3-chloro-6-methoxy-1H-indazole

1443118-73-7 Downstream products

319460-85-0
axitinib

Product Classification

Contact us

1443118-73-7

Product Details;

Manufacturer supply high quality Axitinib Impurity 1443118-73-7 with ISO standards

1443118-73-7 Relevant articles

Preparation method of drug Axitinib for resisting kidney cancer

-

, (2018/05/16)

1443118-73-7 Process route

1443118-73-7 Upstream products

1443118-73-7 Downstream products

Related products

Contact us

Products

Site Map

Contact us